What is Hormonetherapy ?

Hormonetherapy

Hormone therapy is also called as hormonal therapy, hormone treatment, or endocrine therapy. It is used to treat cancer by stopping or slowing cancer's growth and reduce the chance of its return. Helps to Ease cancer symptoms as it may be used to reduce or prevent symptoms in men with prostate cancer who are not able to have surgery or radiation therapy and also treat breast cancers that use hormones to grow.Hormone therapy is most often used along with other cancer treatments which can make a tumor smaller before surgery or radiation therapy (called neoadjuvant therapy), lower the risk that cancer will come back after the main treatment (called adjuvant therapy) and destroy cancer cells that have returned or spread to other parts of your body.

Why Hormone Therapy ?

Cryotherapy is often less invasive than traditional surgical methods. This type of treatment removes damaged or diseased tissue that comes from a variety of medical conditions.It is usually performed through a needle or probe inserted directly into the tumor, reducing recovery time and risks associated with open surgery. Most people recover quickly from the procedure and with little pain.

Some types of cancer where hormonetherapy is commonly used:

• Breast Cancer:

  Hormonetherapy used for metastatic breast cancer to control disease progression. The choice of therapy depends on various factors, including menopausal status, the specific characteristics of the cancer, and overall health.

  Here’s how hormone therapy is used in breast cancer:

  • Ovarian Suppression:Ovarian suppression is a treatment strategy used primarily in premenopausal women with hormone receptor-positive breast cancer..By suppressing ovarian function, the body produces less estrogen. This helps in reducing the stimulation of estrogen-sensitive breast cancer cells.
  • Estrogen Receptor Downregulators (SERDs):SERDs bind directly to estrogen receptors on breast cancer cells. After binding, SERDs cause the estrogen receptors to be degraded and removed from the cancer cells.This degradation decreases the cancer cells' ability to use estrogen for growth and survival.
  • Combination Therapy: In some cases, hormone therapy is combined with other treatments, such as chemotherapy or targeted therapy, depending on the cancer’s characteristics and stage.
  
• Prostate Cancer:

  Reduces levels of male hormones (like testosterone) that fuel cancer growth. Includes medications such as luteinizing hormone-releasing hormone (LHRH) agonists (leuprolide), anti-androgens (bicalutamide), and newer agents like enzalutamide and abiraterone.