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TARGETED THERAPY also called as molecularly targeted therapy is one of the major modalities of medical treatment for cancer. Targeted therapy is a type of cancer treatment that uses drugs or other substances to precisely identify and attack certain types of cancer cells. Targeted therapy act as a form of molecular medicine which blocks the growth of cancer cells by interfering with specific targeted molecules needed for carcinogenesis and tumor growth. The most successful targeted therapies are chemical entities that target or preferentially target a protein or enzyme that carries a mutation or other genetic alteration that is specific to cancer cells and not found in normal host tissue. There are targeted therapies for lung cancer, colorectal cancer, head and neck cancer, breast cancer, multiple myeloma, lymphoma, prostate cancer, melanoma and other cancers.